» Published on
28. Oktober 2013
Researchers discover a new protein fold with a transport tunnel
Biochemists from Bielefeld, Toronto, Boston, and Kiel publish study in ‘Nature’
The
protein LIMP-2 is vital for both humans and animals. If it is absent –
due, for example, to a hereditary disease – substances of an unknown
nature, probably lipids, accumulate in the organism. Up to now,
scientists were unsure what the protein looks like and how exactly it
functions. Privatdozent [senior lecturer] Dr. Michael Schwake from the
Faculty of Chemistry at Bielefeld University (Germany) is doing research
on the protein – and thereby preparing the way for future therapies.
Together with colleagues in Kiel, Toronto, and Boston, he has now
discovered that the protein LIMP 2 possesses a novel protein fold
together with a nanomicroscopically small transport tunnel. The
researchers have published their findings on Sunday (27 October) in the
globally renowned scientific journal ‘Nature’.
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